Aryloxy ester and acid compounds

Details Aryloxy ester and acid compounds Aryloxy ester and acid compounds

C - Chemistry, Metallurgy

07

D

C07D 333/32 (2006.01)

Patent

CA 2410633

This invention is directed to aryloxy ester and acid compounds of the formula (1): Ar-O-(CH2)n-COOR which can be utilized as intermediates in the synthesis of Factor Xa inhibitors to increase their potency and oral activity, and to a method for their production.

La présente invention concerne des composés esters et acides aryloxy de formule (1) : Ar-O-(CH¿2?)¿n?-COOR pouvant être utilisés comme intermédiaires dans la synthèse des inhibiteurs du facteur Xa afin d'augmenter leur activité buccale et thérapeutique, ainsi qu'un procédé de production desdits composés.

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