Aryloxymethylpyrrolidinols and piperidinols having...

Details Aryloxymethylpyrrolidinols and piperidinols having... Aryloxymethylpyrrolidinols and piperidinols having...

C - Chemistry, Metallurgy

07

D

167/208, 260/323

C07D 207/12 (2006.01) A61K 31/445 (2006.01) C07D 211/40 (2006.01) C07D 211/42 (2006.01) C07D 211/48 (2006.01)

Patent

CA 1257277

ARYLOXYMETHYLPYRROLIDINOLS AND PIPERIDINOLS HAVING ANTIDEPRESSANT, ANTIARRHYTEMIC OR HYPOTENSIVE ACTIVITY ABSTRACT OF THE DISCLOSURE Novel aryloxymethylpyrrolidinols and piperidinols are provided of the formula: Image wherein R1 is hydrogen, loweralkyl and phenylloweralkyl; R2 is hydrogen, loweralkyl and acyl; R3 is phenyl, naphthyl, 4-indanyl and 5-indanyl; m is 2 or 3 and n is 1 or 2; and the pharmaceutically acceptable salts thereof, having antiarrhythmic, antidepressant and antihypertensive activity.

473358

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