A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4985 (2006.01) A61P 25/00 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2582663
Novel substituted arylpiperazine derivatives with activity as 5- hydroxytryptamine 1A (5-HT1A ) receptor subtype ligands, to their stereochemical isomers, methods of their preparation, and to their use and to pharmaceutical compositions containing them for the treatment of Parkinson disease, cerebral damage by thromboembolic ictus, craneoencephalic traumatisms, depression, migraine, pain, psychosis, anxiety disorders, aggressive disorders or urinary tract disorders.
La présente invention concerne de nouveaux dérivés substitués d~arylpipérazine présentant une activité en tant que ligands du sous-type de récepteur de la 5-hydroxytryptamine 1A (5-HT1A ), à leurs stéréo-isomères, à des procédés de leur préparation, et à leur utilisation et à des compositions pharmaceutiques les contenant destinées au traitement de la maladie de Parkinson, des lésions cérébrales dues à un accident thrombo-embolique, des traumatismes crânio-encéphaliques, des dépressions, des migraines, des douleurs, des psychoses, des troubles de l~anxiété, des désordres agressifs ou des troubles du système urinaire.
Benhamu Salama Bellinda
Lopez Rodriguez Maria Luz
Valhondo Falcon Margarita
Robic
Schwarz Pharma S.l.
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