Arylpiperazines having activity at the serotonin 1a receptor

Details Arylpiperazines having activity at the serotonin 1a receptor Arylpiperazines having activity at the serotonin 1a receptor

C - Chemistry, Metallurgy

07

D

C07D 295/092 (2006.01) A61K 31/495 (2006.01) C07D 213/74 (2006.01) C07D 295/088 (2006.01) C07D 295/104 (2006.01) C07D 295/108 (2006.01) C07D 401/04 (2006.01) C07C 45/00 (2006.01) C07C 45/29 (2006.01) C07C 45/40 (2006.01) C07C 45/51 (2006.01) C07C 45/59 (2006.01) C07C 45/68 (2006.01) C07C 49/563 (2006.01) C07C 49/577 (2006.01) C07C 49/583 (2006.01) C07C 49/86 (2006.01)

Patent

CA 2315227

A series of arylpiperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.

L'invention concerne une série de composés d'arylpipérazine, constituant des médicaments efficaces pour traiter les états liés ou dus au récepteur 1A de la sérotonine. Ces composés constituent des antagonistes particulièrement efficaces de ce récepteur, et sont particulièrement utiles pour soulager les symptômes du syndrome de sevrage à la nicotine ou au tabac.

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