Arylpiperidine derivatives and use thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/14 (2006.01) A61K 31/445 (2006.01) C07D 405/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2324550

Arylpiperidine derivatives represented by general formula (I) or pharmacologically acceptable salts thereof, both having an antipsychotic action: wherein D represents carbon or nitrogen; E represents CH or nitrogen; G represents oxygen, sulfur, nitrogen, or NH; Y1 represents hydrogen or a halogen; n is an integer of 1 to 4; and R1 represents any of the groups represented by the formulae (i) to (iv) defined in the specification.

L'invention concerne des dérivés d'arylpipéridine, représentés par la formule générale (I), ou des sels de ceux-ci, acceptables sur le plan pharmacologique, ces composés et sels possédant une action antipsychotique. Dans la formule (I), D représente carbone ou azote, E représente CH ou azote, G représente oxygène, soufre, azote ou NH, Y?1¿ représente hydrogène ou un halogène, n est un nombre entier compris entre 1 et 4 et R?1¿ représente l'un quelconque des groupes correspondant aux formules (i) à (iv) définies dans la description.

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