Arylsulfonyl benzodioxanes useful for modulating the 5-ht6...

C - Chemistry – Metallurgy – 07 – D

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C07D 319/20 (2006.01) A61K 31/357 (2006.01) A61P 25/00 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2566196

Compounds of the formula (I) or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein m, n, p, Ar, X, R1, R2, R3, R4, R5 and R6 are as defined herein as well as compositions comprising these compounds and uses of the subject compounds for the preparation of medicaments for treating psychoses, schizophrenia, manic depressions, neurological disorders, memory disorders, attention deficit disorder, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease, food uptake disorders, Huntington's disease and gastrointestinal tract.

L'invention concerne des composés de la formule I ; ou des sels, des solvates ou des promédicaments pharmaceutiquement acceptables de ceux-ci, dans laquelle m, n, p, Ar, X, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ et R?6¿ sont tels que définis dans le descriptif, ainsi que des compositions renfermant ces composés et leurs utilisations pour préparer des médicaments destinés à traiter les psychoses, la schizophrénie, les manie-dépressions, les troubles neurologiques, les troubles de la mémoire, le trouble déficitaire de l'attention, la maladie de Parkinson, la sclérose latérale amyotrophique, la maladie d'Alzheimer, les troubles d'absorption des aliments, la maladie de Huntington et le tractus gastro-intestinal.

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