Arylsulfonyl derivatives with 5-ht6 receptor affinity

Details Arylsulfonyl derivatives with 5-ht6 receptor affinity Arylsulfonyl derivatives with 5-ht6 receptor affinity

C - Chemistry, Metallurgy

07

D

C07D 295/02 (2006.01) A61K 31/495 (2006.01) A61P 25/24 (2006.01) C07D 295/096 (2006.01)

Patent

CA 2456250

This invention relates to compounds which have generally HT6 receptor affinity and which are represented by formula (1) ,wherein Ar, R 1 and R2 are as defined in the specification, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, their use as therapeutic agents, and methods of preparation thereof.

Cette invention concerne des composés, ainsi que des sels ou des solvates pharmaceutiquement acceptable de ces composés, qui présentent généralement une affinité pour le récepteur HT6 et qui sont représentés par la formule (1). Dans cette formule Ar, R ?1¿ et R?2¿ sont tels que définis dans les spécifications. L'invention concerne également des compositions renfermant de tels composés, leur utilisation à des fins thérapeutiques et leurs méthodes de préparation.

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