C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01)
Patent
CA 2263353
The present invention relates to a novel arylsulfonylimidazolone derivative represented by formula (I) which shows a superior antineoplastic activity in contrast to the known sulfonylurea antitumor agents as well as little side effect; and its pharmaceutically acceptable salt and stereoisomer, in which <u>--</u>, R1 and R2 are as defined in the specification.
L'invention se rapporte à un nouveau dérivé d'arylsulfonylimidazoline qui répond à la formule suivante (I) où <u>--</u>, R¿1? et R¿2? sont tels qu'ils sont définis dans la description, et qui possède une action antinéoplastique supérieure à celle des agents anti-tumoraux connus à base de sulfonylurée tout en ayant peu d'effets secondaires; l'invention se rapporte également à un sel pharmaceutiquement acceptable et à un stéréo-isomère dudit dérivé.
Choi Chung Ha
Choi Dong Rack
Chung Yong Ho
Hwang Hyun Sook
Jung Sang Hun
Dong Wha Pharm. Ind. Co. Ltd.
Robic
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