Arylsulphonamide-substituted benzimidazole derivatives,...

Details Arylsulphonamide-substituted benzimidazole derivatives,... Arylsulphonamide-substituted benzimidazole derivatives,...

A - Human Necessities

61

K

A61K 31/4184 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61K 31/55 (2006.01) A61K 31/5513 (2006.01) A61P 29/00 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2379557

The invention relates to arylsulphonamide-substituted benzimidazole derivatives of general formula (I) Image wherein the groups R1, R2, R3 and R4 may have the meanings given in the claims and specification, processes for preparing them as well as the use of arylsulphonamide-substituted benzimidazole derivatives as pharmaceutical compositions, particularly as pharmaceutical compositions with a tryptase- inhibiting activity.

L'invention concerne des dérivés de benzimidazole portant comme substituant un arylsulfonamide, de formule générale (I), dans laquelle les restes R<1>, R<2>, R<3> et R<4> ont les significations données dans les revendications et dans la description. L'invention concerne en outre un procédé de fabrication de ces composés, ainsi que l'utilisation des dérivés de benzimidazole portant comme substituant un arylsulfonamide, comme médicaments, en particulier comme médicaments à effet inhibiteur de la tryptase.

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