Arylsulphonyl-substituted...

Details Arylsulphonyl-substituted... Arylsulphonyl-substituted...

C - Chemistry, Metallurgy

07

D

C07D 209/88 (2006.01) A61K 31/403 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2461369

The invention provides compounds of Formula (I) for use in treating conditions in which 5-HT6 receptors are involved such as in anxiety, depression, schizophrenia, Alzheimer's disease, stress-related disease, panic, a phobia, obsessive compulsive disorder, obesity, post-traumatic stress syndrome, epilepsy, and other CNS disorders, Formula (I), wherein [b] is a single or double bond and R1, R2, R3, R4, R5, R6, R7, X, Y and Z have any definition discussed herein.

L'invention porte sur des composés de formule (I) destinés à être utilisés dans le traitement d'états tels que l'anxiété, la dépression, la schizophrénie, la maladie d'Alzheimer, les maladies relatives au stress, les crises de panique, la phobie, les troubles obsessionnels compulsifs, l'obésité, le syndrome du stress post-traumatique, l'épilepsie et autres troubles du système nerveux central. Dans la formule (I), [b] représente une liaison simple ou double et R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, R¿6?, R¿7?, X, Y et Z sont tels que définis dans la demande.

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