C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/225, 167/234
C07D 417/06 (2006.01) A61K 31/425 (2006.01) A61K 31/435 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2016181
Arylthiazolylimidazoles as 5HT3 antagonists useful in the treatment of nausea, anxiety, pain, schizophrenia and gastrointestinal disorders. Ar-HET-CH2-X wherein Ar is pyridyl, 3-indolyl; 8-quinolyl, phenyl or mono- or disubstituted phenyl wherein the substituent is each methyl, methoxy, fluoro, chloro or bromo; HET is thiazolyl; and X is imidazole or mono- or dimethylimidazole.
Les arylthiazolylimidazoles sont utiles, comme antagonistes de 5HT3, pour le traitement de la nausée, de l'anxiété, de la douleur, de la schizophrénie et des troubles gastro-intestinaux. Dans Ar-HET-CH2-X, Ar est un groupe pyridyle, 3-indolyle, 8-quinolyle, phényle ou phényle avec mono- ou disubstitution, le substituant étant un groupe méthyle, méthoxy, fluoro, chloro ou bromo; HET est un thiazolyle; enfin, X est un imidazole ou un mono- ou diméthylimidazole.
Nagel Arthur A.
Rizzi James P.
Rosen Terry J.
Pfizer Inc.
Smart & Biggar
LandOfFree
Arylthiazolylimidazoles as 5ht3 antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Arylthiazolylimidazoles as 5ht3 antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Arylthiazolylimidazoles as 5ht3 antagonists will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1643431