Arylthio compounds as antibacterial and antiviral agents

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 323/42 (2006.01) A61K 31/16 (2006.01) A61K 31/166 (2006.01) A61K 31/167 (2006.01) A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61K 31/215 (2006.01) A61K 31/216 (2006.01) A61K 31/225 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) A61K 31/66 (2006.01) C07C 323/22 (2006.01) C07C 323/47 (2006.01) C07C 323/62 (2006.01) C07C 323/63 (2006.01) C07C 323/65 (2006.01) C07C 323/67 (2006.01) C07D 207/08 (2006.01) C07D 207/12 (2006.01) C07D 207/14 (2006.01) C07D 207/16 (2006.01) C07D 211/62 (2006.01) C07D 213/

Patent

CA 2193845

Arylthiol and dithiobisarylamide antibacterial and antiviral agents have general formula (I) where A is monocyclic or bicyclic aryl which can contain up to 3 heteroatoms selected from O, S, and N, R1 and R2 are substituent groups, X is (a), (b), (c), or SO2NR4Z, Y is H or SZ when n is 1, a single bond when n is 2; R4 and Z can be hydrogen or alkyl.

L'invention concerne des agents antibactériens et antiviraux à base d'arylthiol et de dithiobisarylamide représentés par la formule générale (I). Dans cette formule, A est un aryle monocyclique ou bicyclique qui peut renfermer jusqu'à 3 hétéroatomes choisis parmi O, S et N; R?1¿ et R?2¿ sont des groupes substituants; X est un groupe (a), (b), (c) ou SO¿2?NR?4¿Z; Y représente H ou SZ lorsque n est égal à 1, une liaison simple lorsque n est égal à 2; R?4¿ et Z peuvent représenter chacun hydrogène ou alkyle.

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