C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/16 (2006.01) A61K 31/4375 (2006.01) A61K 31/4745 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01)
Patent
CA 2393965
The invention concerns a pharmaceutical composition comprising an efficient amount of a compound selected among the compounds of formulae (I) and (Ia) wherein: R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, R¿6? and R¿7? are as defined in Claim 1. Said compounds have interesting cytotoxic properties leading to a therapeutic use as antitumoral medicines.
La présente invention concerne une composition pharmaceutique comprenant une quantité efficace d'un composé choisi parmi les composés de formules (I) et (Ia), dans lesquelles, R1, R2, R3, R4, R5, R6 et R7 sont tels que définis à la revendication 1. Ces composés possèdent des propriétés cytotoxiques intéressantes conduisant à une application thérapeutique comme médicaments anti-tumoraux.
Bastide Jean
Darro Francis
Delfourne Evelyne
Frydman Armand
Kiss Robert
Fetherstonhaugh & Co.
Laboratoire L. Lafon
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