C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 498/18 (2006.01) A61K 31/395 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2668134
Provided is ascomycin that has a low level of an FK523 impurity, and pimecrolimus that has a low level of a 32-deoxy-32-epichloro-FK523 impurity, methods of preparing them, and the use of such pimecrolimus for preparing a pharmaceutical composition.
L'invention concerne une ascomycine ayant un faible niveau d'une impureté FK523, et un pimécrolimus ayant un faible niveau d'une impureté 32-désoxy-32-épichloro-FK523, leurs procédés de préparation et l'utilisation d'un tel pimécrolimus pour la préparation d'une composition pharmaceutique.
Csorvasi Andrea
Gyollai Viktor
Keri Vilmos
Kovacs Piroska
Meszarosne Sos Erzsebet
Heenan Blaikie Llp
Teva Gyogyszergyar Zartkoerueen Muekoedoe Reszvenytarsasag
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