Ascomycins

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 19/01 (2006.01) A61K 31/70 (2006.01) C07D 498/18 (2006.01)

Patent

CA 2216562

The invention provides novel ascomycins bearing one or more physiologically hydrolyzable and acceptable acceptable oxycarbonyl moieties or carboxy moieties, such compounds being found useful as pharmaceuticals, especially in the treatment of asthma and dermatitis. Methods of producing the compounds and pharmaceutical compositions comprising the compounds are also provided.

L'invention décrit de nouvelles ascomycines comportant une ou plusieurs fractions oxycarbonyle ou carboxy physiologiquement hydrolysables et acceptables, ces composés étant utilisés comme produits pharmaceutiques, particulièrement dans le traitement de l'asthme et de la dermatite. L'invention décrit également des procédés de fabrication des composés et de ces compositions pharmaceutiques les contenant.

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