Ascophyllum compositions and methods

Details Ascophyllum compositions and methods Ascophyllum compositions and methods

A - Human Necessities

61

K

A61K 31/737 (2006.01) A61K 31/05 (2006.01) A61K 31/09 (2006.01)

Patent

CA 2541747

The invention provides extracts of brown seaweed of the genus Ascophyllum that have valuable pharmacological properties. In particular, compositions of the invention are useful for e.g.: inhibiting alpha-glucosidase activity; preventing or treating conditions mediated by alpha-glucosidase activity; reducing blood glucose levels; preventing or treating diabetes; modulating glucose uptake in adipocytes; preventing or treating obesity; scavenging free radicals; stimulating the immune system; activating macrophages; preventing or treating condition mediated by macrophage activation; and modulating nitric oxide production by macrophages. Methods for using the Ascophyllum extracts of the invention are provided, as are kits comprising Ascophyllum extracts of the invention and instructions for using the extracts.

La présente invention propose des extraits d'algue brune du genre Ascophyllum qui ont des propriétés pharmacologiques souhaitables. En particulier, les compositions de l'invention sont utiles pour, par exemple : inhiber l'activité alpha-glucosidase ; prévenir ou traiter des pathologies médiées par l'activité alpha-glucosidase ; diminuer les taux sanguins de glucose ; prévenir ou traiter le diabète ; moduler l'absorption de glucose dans les adipocytes ; prévenir ou traiter l'obésité ; piéger les radicaux libres ; stimuler le système immunitaire ; activer les macrophages ; prévenir ou traiter une pathologie médiée par l'activation des macrophages ; et moduler la production d'oxyde nitrique par les macrophages. Des procédés pour utiliser les extraits d'Ascophyllum de l'invention sont proposés, ainsi que des kits comprenant des extraits d'Ascophyllum de l'invention et des instructions pour utiliser les extraits.

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