Ascorbate resistant composition and test device for...

Details Ascorbate resistant composition and test device for... Ascorbate resistant composition and test device for...

G - Physics

01

N

G01N 33/84 (2006.01) C12Q 1/54 (2006.01)

Patent

CA 2058702

ABSTRACT OF THE DISCLOSURE A dip-and-read type indicator as described which is capable of detecting the presence of a component in a test solution, despite the presence of an interfering substance. The invention particularly directed to the detection of glucose in urine samples in the presence of a reducing agent, such as ascorbic acid. The invention uses mercury (II) oxide complexes with various ligands such as alanine, lysine, Tris/glutamate, Tris/succinate, DL-.beta.-Aminobutyric acid, and DL-?-Aminobutyric acid. These ligands were found to be suitable because of their ability to complex with HgO, their ability to chemically react with the interfering substance, and their ability to control the pH of the dip solution. MS-1611

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