Ascorbic acid composition and method for treatment of aging...

A - Human Necessities – 61 – K

Patent

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A61K 31/195 (2006.01) A61K 31/22 (2006.01) A61K 31/235 (2006.01) A61K 31/315 (2006.01) A61K 31/34 (2006.01) A61K 31/375 (2006.01) A61K 33/04 (2006.01) A61K 33/30 (2006.01) A61K 38/06 (2006.01)

Patent

CA 2366996

An ascorbic acid-based composition and related method for the treatment of aging or photo-damaged skin is disclosed. The composition includes water and ascorbic acid, at least a portion of which has generally been pretreated by being dissolved under relatively high temperature and concentration conditions. The composition typically includes at least about 5.0 %(w/v) ascorbic acid and may advantageously be formulated to have a pH above 3.5. Generally, the composition also includes non-toxic zinc salt, tyrosine compound, and/or cosmetically acceptable carrier. In addition, the composition may include an anti-inflammatory compound, such as aminosugar and/or sulfur-containing anti-inflammatory compound. The topical composition may be in the form of a serum, a hydrophilic lotion, an ointment, a cream, or a gel.

Cette invention concerne une composition à base d'acide ascorbique et une méthode connexe de traitement du vieillissement de la peau et de lésions cutanées provoquées par la lumière. Cette composition renferme de l'eau et de l'acide ascorbique dont une partie au moins a été en général pré-traitée par dissolution à une température relativement élevée et par concentration. Elle contient le plus souvent au moins 5,0 % (m/v) d'acide ascorbique et peut être avantageusement élaborée avec un pH supérieur à 3,5. En général, cette composition comprend également un sel de zinc non toxique, un composé tyrosine et/ou un excipient acceptable au plan cosmétique. De plus, elle peut inclure un composé anti-inflammatoire tel qu'un aminosucre et/ou un composé anti-inflammatoire renfermant du soufre. La composition selon l'invention peut se présenter sous forme de sérum, de lotion hydrophile, d'onguent, de crème ou de gel.

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