Ascorbic acid intermediates

C - Chemistry – Metallurgy – 07 – C

Patent

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260/488, 260/526

C07C 69/67 (2006.01) C07D 307/62 (2006.01) C07D 493/04 (2006.01) C07H 7/027 (2006.01) C07H 9/04 (2006.01)

Patent

CA 1096397

Abstract of the Disclosure A synthetic route to ascorbic acid is provided in which a 3,5:4,6-protected derivative of gulonic acid is prepared from gulono-1,4-lactone. Oxidation of the derivative and hydrolysis of the resulting product affords 2-ketogulonic acid or ester thereof which can be readily converted to ascorbic acid by known methods.

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