Aspartate carbamyltransferase as herbicidal target

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/54 (2006.01) C12N 9/10 (2006.01) C12N 15/11 (2006.01) C12N 15/82 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2400766

The present invention relates to the use of DNA sequences of plant origin. Said sequences code for a polypeptide with aspartate carbamyltransferase (E.C.2.1.3.2) activity. The aim of the invention is to produce a test system for finding inhibitors of the aspartate carbamyltransferase. According to the invention, it has been proven for the first time and by means of the antisense technology that aspartate carbamyltransferase is a herbicidal target.

La présente invention concerne l'utilisation de séquences d'ADN d'origine végétale codant pour un polypeptide présentant une activité d'aspartate-carbamyle transférase (E.C.2.1.3.2) pour la production d'un système de test permettant de détecter des inhibiteurs de l'aspartate-carbamyle transférase. Pour la première fois, il a été montré, à l'aide de la technologie antisens, que l'aspartate-carbamyle transférase constitue une cible pour des herbicides.

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