C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 271/22 (2006.01) C07C 233/47 (2006.01) C07C 233/51 (2006.01) C07C 275/16 (2006.01) C07C 311/03 (2006.01) C07C 311/06 (2006.01) C07C 311/19 (2006.01) C07C 317/04 (2006.01) C07C 317/44 (2006.01) C07C 323/52 (2006.01) C07C 327/32 (2006.01) C07D 207/08 (2006.01) C07D 207/27 (2006.01) C07D 207/28 (2006.01) C07D 209/08 (2006.01) C07D 209/18 (2006.01) C07D 211/34 (2006.01) C07D 211/76 (2006.01) C07D 213/55 (2006.01) C07D 213/75 (2006.01) C07D 217/24 (2006.01) C07D 233/36 (2006.01) C07D 239/10 (2006.01) C07D 3
Patent
CA 2268098
The present invention relates to compounds that are inhibitors of interleukin- 1.beta. converting enzyme that have formula (I). This invention also relates to a method of treatment of stroke, inflammatory diseases, reperfusion injury, Alzheimer's disease, and shigellosis, and to a pharmaceutically acceptable composition that contains a compound that is an inhibitor of interleukin- 1.beta. converting enzyme.
La présente invention se rapporte à des composés qui agissent en tant qu'inhibiteurs de l'enzyme de conversion de l'interleukine-1 beta et qui répondent à la formule (I). L'invention concerne également une méthode de traitement de l'ictus, des maladies inflammatoires, de la lésion de perfusion répétée, de la maladie d'Alzheimer et de la shigellose, ainsi qu'une composition pharmaceutiquement acceptable qui comprend un composant fonctionnant comme un inhibiteur de l'enzyme de conversion de l'interleukine-1 beta .
Albrecht Hans-Peter
Allen Hamish John
Brady Kenneth Dale
Caprathe Bradley William
Gilmore John Lodge
Abbott Gmbh & Co. Kg.
Basf Aktiengesellschaft
Macrae & Co.
Warner-Lambert Company
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