Aspartyldipeptide derivatives and sweetener

Details Aspartyldipeptide derivatives and sweetener Aspartyldipeptide derivatives and sweetener

C - Chemistry, Metallurgy

07

K

C07K 5/072 (2006.01) A23L 1/236 (2006.01)

Patent

CA 2153551

The invention is concerned with novel aspartyldipeptide derivatives of the general formula (I): L-Asp-X-NH-C*HR1R2 (I) wherein R1 represents an alkyl group having from 1 to 6 carbon atoms or an alkoxymethyl group having from 2 to 7 carbon atoms; R2 represents a phenyl group, a benzyl group, a cyclohexyl group or a cyclohexylmethyl group; the structure having the C* atom being of (S) form when R1 is an alkyl group or of (R) form when R1 is an alkoxymethyl group; X represents a residue of a D-.alpha.- amino acid or DL-.alpha.-amino acid, or a residue of a cyclic or acyclic .alpha.,.alpha.-dialkylamino acid having from 3 to 6 carbon atoms; the bond between L-Asp and X being an .alpha.-bond, and their salts. The compounds according to the invention are highly stable and safe and have a high sweetness potency.

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