Aspergillus promotors for expressing a gene in a fungal cell

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/80 (2006.01) C12N 1/15 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2599180

The present invention relates to isolated promoter DNA sequences, to DNA constructs, vectors, and host cells comprising these promoters in operative association with coding sequences. The present invention also relates to methods for expressing a gene and/or producing a biological compound using the new promoters isolated. The present invention also relates to methods for altering the transcription level and/or regulation of an endogenous gene using the new promoter of the invention.

La présente invention concerne des séquences isolées d'ADN promoteur, des constructions d'ADN, des vecteurs et des cellules hôtes comprenant ces promoteurs en association fonctionnelle avec des séquences codantes. Cette invention porte également sur des méthodes d'expression d'un gène et/ou de production d'un composé biologique au moyen des nouveaux promoteurs isolés ainsi que sur des méthodes d'altération du niveau de transcription et/ou de la régulation d'un gène endogène au moyen du nouveau promoteur selon l'invention.

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