Assay and cell line for the identification of growth hormone...

G - Physics – 01 – N

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G01N 33/50 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12N 15/79 (2006.01) C12Q 1/68 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2270179

A stably transformed cell line is provided for the identification of growth hormone mimetics wherein the cell line is transformed to express a reporter gene construct comprised of a promoter and a growth hormone response element operatively linked to a reporter gene.

L'invention a trait à une lignée cellulaire transformée de manière stable et permettant d'identifier des mimétiques d'hormone de croissance, la lignée cellulaire étant transformée pour exprimer un produit de recombinaison de gène marqueur comprenant un promoteur et un élément de réponse d'hormone de croissance lié fonctionnellement à un gène marqueur.

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