Assay and kit for the detection of chromosomal abnormalities

Details Assay and kit for the detection of chromosomal abnormalities Assay and kit for the detection of chromosomal abnormalities

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2109518

2109518 9219775 PCTABS00017 A target sequence including a chromosomal translocation or other abnormality is detected by reacting the target sequence, under hybridising conditions in a homogeneous phase, with excess amounts of capture and reporter oligonucleotide probes which are respectively complementary to different regions of the target sequence; and separating and detecting any resultant hybrid that has both labels.

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