Assay conjugate and uses thereof

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 1/04 (2006.01) C07K 1/13 (2006.01) C07K 17/06 (2006.01) C07K 17/10 (2006.01) G01N 33/531 (2006.01) G01N 33/533 (2006.01) G01N 33/534 (2006.01) G01N 33/546 (2006.01) G01N 33/548 (2006.01)

Patent

CA 2498142

The subject invention relates to a conjugate which may be used for the detection of an analyte in a test sample. In particular, the conjugate comprises a heterophilic carrier, at least 10 label groups, an analyte- specific binding pair member (e.g., an antibody or antigen with complexes with the antigen or antibody of interest, respectively) as well as a heterophilic linker which indirectly attaches the acridinium-containing compounds to the analyte-specific binding pair member.

L'invention porte sur un conjugué pouvant être utilisé dans la détection d'un analyte dans un échantillon test. Ce conjugué comprend notamment un excipient hétérophile, au moins 10 groupes d'étiquettes, un élément d'appariement se liant de manière spécifique à un analyte (tel qu'un anticorps ou un antigène qui se complexe à l'antigène ou à l'anticorps concerné, respectivement), ainsi que sur un lieur hétérophile qui fixe indirectement les composés contenant acridinium à l'élément d'appariement se liant de manière spécifique à l'analyte.

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