C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/44 (2006.01) A61K 39/005 (2006.01) C07K 1/22 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2139632
An assay to confirm the presence of antibodies to T. cruzi in a test sample. The assay comprises de- tecting the presence of antibody to three T. cruzi anti- gens, Gp90, Gp60/50 and LPPG in a test sample. The presence of antibody in the test sample to at least two of three T. cruzi antibodies is indicative of a con- firmed reactive sample. Also provided are diagnostic reagents for detection of T. cruzi, a process for purify- ing GP60/50, a process for linking a protein and LPPG, and diagnostic test kits for use when assaying for antibodies to T. cruzi.
Pan Alfred A.
Winkler Martin A.
Abbott Laboratories
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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