Assay for detection of renal cell carcinoma

G - Physics – 01 – N

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G01N 33/574 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2516588

Methods for diagnosing and monitoring renal cell carcinoma in a subject comprising detecting kallikrein polypeptides, or polynucleotides encoding the polypeptides in a sample from the subject. The kallikrein polypeptides include kallikrein 5, kallirekin 6, kallikrein 10, and kallikrein 11.

Cette invention concerne des méthodes de diagnostic et de surveillance d'un hypernéphrome chez un sujet, lesquelles méthodes consistent à détecter des polypeptides de kallicréine ou des polynucléotides codant ces polypeptides dans un échantillon prélevé sur le sujet. Les polypeptides de kallicréine comprennent la kallicréine 5, la kallicréine 6, la kallicréine 10 et la kallicréine 11.

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