Assay for drug discovery based on in vitro differentiated cells

Details Assay for drug discovery based on in vitro differentiated cells Assay for drug discovery based on in vitro differentiated cells

C - Chemistry, Metallurgy

12

Q

C12Q 1/02 (2006.01) C12N 5/077 (2010.01) C12Q 1/68 (2006.01)

Patent

CA 2565858

Provided are assay systems for determining the therapeutic or toxic effect of a putative drug based on assaying its activity in cells which have been differentiated in vitro from stem cells, and induced to display a phenotype that resembles a disease to be treated.

L'invention concerne des systèmes de dosage pour la détermination de l'effet thérapeutique ou toxique d'un médicament putatif reposant sur le dosage de son activité dans des cellules qui ont été différenciées in vitro à partir de cellules souches et induites de manière à présenter un phénotype qui ressemble à une maladie à traiter.

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