C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01) A61K 49/00 (2006.01) C12Q 1/44 (2006.01)
Patent
CA 2362305
An assay for emetic activity among inhibitors of type 4 phosphodiesterase (PDE 4) is disclosed. The assay comprises: (A) administering to a test mammal an anesthetic compound in an amount sufficient to cause an anesthetic effect; (B) administering to the test mammal a test compound that has PDE 4 inhibitory activity; (C) observing the test mammal for changes in the anesthetic effect, and(D) correlating any change in the anesthetic effect observed in the anesthetized test mammal to a standard.
L'invention a trait à une méthode destinée à l'activité émétique parmi d'inhibiteurs de phosphodiestérase de type 4 (PDE 4). Cette méthode consiste à: (A) administrer à un mammifère test un composé anesthésique en quantité suffisante pour occasionner un effet anesthésique, (B) administrer au mammifère test un composé test qui possède une activité inhibitrice PDE 4, (C) observer les changements de l'effet anesthésique chez ce mammifère, et (D) comparer tout changement de l'effet anesthésique observé chez ce mammifère test anesthésié à une norme.
Chan Chi Chung
Robichaud Annette
Savoie Chantal
Merck Frosst Canada & Co./merck Frosst Canada & Cie
Merck Frosst Canada Ltd.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
LandOfFree
Assay for emetic activity does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Assay for emetic activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Assay for emetic activity will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1740361