Assay for growth differentiation factor 9

G - Physics – 01 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

G01N 33/68 (2006.01) G01N 33/50 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2325019

The present invention relates to a method of identifying an agent which alters (inhibits, enhances) activity of GDF-9. The method involves combining cells having a receptor for GDF-9 and a gene, wherein expression of the gene is regulated by binding of GDF-9 to the receptor; GDF-9; and an agent to be assessed. The combination produced is maintained under conditions appropriate for binding of GDF-9 to the receptors on the cells. The extent to which binding of GDF-9 to the receptors on the cells occurs is then determined, wherein binding of GDF-9 to the receptor to a lesser or greater extent in the presence of the agent to be assessed than in its absence, is indicative of an agent which alters GDF-9 activity.

La présente invention concerne une méthode permettant d'identifier un agent modifiant (inhibant, favorisant) l'activité du facteur 9 de différenciation de croissance (GDF-9). Ladite méthode consiste à combiner des cellules présentant un récepteur pour GDF-9 et un gène, l'expression du gène étant régulée par liaison du GDF-9 au récepteur; GDF-9; et un agent à identifier. La combinaison produite est maintenue dans des conditions appropriées à la liaison du GDF-9 aux récepteurs présents sur les cellules. On détermine ensuite le degré de liaison entre GDF-9 et les récepteurs présents sur les cellules, le degré de liaison du GDF-9 au récepteur, plus ou moins important selon la présence ou l'absence de l'agent à identifier, étant révélateur d'un agent modifiant l'activité de GDF-9.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Assay for growth differentiation factor 9 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Assay for growth differentiation factor 9, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Assay for growth differentiation factor 9 will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1823651

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.