C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/63 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2603585
The present invention relates to an assay for the identification of biologically active compounds, in particular to a reporter gene assay for the identification of compounds, which have an effect on mRNA stability. More particularly, the present invention relates to a reporter gene expression system and cell lines comprising said expression system. The invention further relates to compounds which destabilise mRNA.
La présente invention a trait à un dosage pour l'identification de composés biologiquement actifs, notamment à un dosage de gènes rapporteurs pour l'identification de composés, présentant un effet sur la stabilité de l'ARNm. Plus particulièrement, la présente invention a trait à un système d'expression de gènes rapporteurs et des lignées cellulaires comportant ledit système d'expression. L'invention a également trait à des composés qui déstabilisent l'ARNm.
Cheneval Dominique
Kastelic Tania
Mbm Intellectual Property Law Llp
Novation Pharmaceuticals Inc.
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