C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 14/195 (2006.01)
Patent
CA 2412187
The present invention relates to a method of identifying modulators of Borrelia telomere resolvase. The method involves incubating the Borrelia telomere resolvase enzyme, ResT, in the presence of a test substance and a telomere resolution substrate comprising a functional replicated telomere. Substances identified using the method of the invention may be potent inhibitors of Borrelia infection.
Chaconas George
Kobryn Kerri
Tourand Yvonne M.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Chaconas George
Kobryn Kerri
Tourand Yvonne M.
University Of Western Ontario
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