Assay for in vitro measurement of amino-telopeptides of type...

Details Assay for in vitro measurement of amino-telopeptides of type... Assay for in vitro measurement of amino-telopeptides of type...

C - Chemistry, Metallurgy

07

K

167/37, 530/7.02

C07K 14/78 (2006.01) C07K 7/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 1340523

Methods of determining type I collagen degradation in vivo are provided by determining the presence or concentration of a peptide in a body fluid, the peptide being an N-terminal type I collagen telopeptide fragment containing a hydroxylysyl pyridinoline or lysyl pyridinoline cross-link. Kits comprising an immunological binding partner which binds to a type I collagen telopeptide fragmentused to assay these peptides in a body fluid are also described.

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