Assay for inhibitors of farnesyl-protein transferase

Details Assay for inhibitors of farnesyl-protein transferase Assay for inhibitors of farnesyl-protein transferase

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C12N 1/21 (2006.01) C12N 9/10 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2147496

The present invention relates to an assay useful in determining the farnesyl-protein transferase inhibitory activity of pharmaceutical agents. The assay employs purified human farnesyl-protein transferase which is prepared by gene expression in Escherichia coli.

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