Assay for lyme disease

Details Assay for lyme disease Assay for lyme disease

G - Physics

01

N

G01N 33/569 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2060232

P-1774 IMPROVED ASSAY FOR LYME DISEASE ABSTRACT OF THE DISCLOSURE Diagnosis of Lyme disease by immunoassay for anti-Borrelia burgdorferi antibodies in the serum of a patient includes adsorption of crossreactive antibodies in the serum with antigen of Acinetobacter calcoaceticus or Treponema phagedensis prior to binding of anti-Borrelia antibodies to Borrelia burgdorferi antigen absorbed onto a solid support. The preferred assay is a flow-through assay using a porous membrane as the support and a dye-loaded liposome conjugated to a goat antihuman antibody for detection. The invention includes a kit of materials for performing the assay.

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