Assay for the identification of protein sic inhibitor

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/18 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2516130

An assay method for an anti-bacterial agent comprising: (a) providing as a first component protein SIC; (b) providing as a second component an antibacterial peptide; (c) contacting the first component with a test substance in the presence of the second component; and (d) determining the interaction or activity of the first component with the second component to determine thereby whether a test substance is an effective anti-bacterial agent.

L'invention concerne un procédé d'analyse d'un agent antibactérien. Ce procédé consiste : (a) à utiliser en tant que premier composant une protéine SIC; (b) à utiliser en tant que deuxième composant un peptide antibactérien; (c) à mettre en contact le premier composant avec une substance d'essai en présence du deuxième composant; et (d) à déterminer l'interaction ou l'activité du premier composant avec le deuxième composant de manière à déterminer si une substance d'essai constitue un agent antibactérien efficace.

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