Assay for vitamin b12 absorption and method of making...

A - Human Necessities – 61 – K

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A61K 51/00 (2006.01) C12P 19/42 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2623215

The invention provides methods for labeling vitamin B 12 with14C, 13C tritium, and deuterium. When radioisotopes are used, the invention provides for methods of labeling B 12 with high specific activity. The invention also provides labeled vitamin B 12 compositions made in accordance with the invention.

L'invention concerne des méthodes permettant d'étiqueter une vitamine B 12 avec du tritium 14C, 13C et du deutérium. Lorsque les radio-isotopes sont utilisés, l'invention concerne des méthodes permettant d'étiqueter B 12 avec une activité spécifique élevée. L'invention concerne également des compositions de vitamine B 12 étiquetée fabriquées conformément à l'invention.

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