Assay for ykl-40 as a marker for degradation of mammalian...

Details Assay for ykl-40 as a marker for degradation of mammalian... Assay for ykl-40 as a marker for degradation of mammalian...

G - Physics

01

N

G01N 33/574 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/53 (2006.01) G01N 33/564 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2164498

The invention is a method of identifying the presence of a disease state in a mammal which is associated with degradation of connective tissue in the mammal which contains the protein known as YKL-40. The method is a competitive immunoassay for YKL-40. It can be used, for example, to identify the presence of inflammatory or degenetative joint disease and tumor metastasis (to the extent it can be correlated to serum YKL-40 levels). Serum YKL-40 levels as detected and quantified by the inventive method are also suggestive of the prognosis for the length of survival in breast cancer patients following recurrence and/or metastasis of their cancers.

L'invention se rapporte à un procédé d'identification d'un état pathologique chez un mammifère qui est associé à la dégradation du tissu conjonctif du mammifère, tissu conjonctif qui contient la protéine connue sous l'appellation YKL-40. Le procédé est un dosage immunologique compétitif s'appliquant à l'YKL-40. Il peut être utilisé, par exemple, pour identifier un état inflammatoire ou l'arthrose ainsi que des métastases tumorales (jusqu'à ce qu'il puisse correspondre aux niveaux sériques d'YKL-40). Les niveaux sériques d'YKL-40 tels que détectés et quantifiés par le procédé de l'invention et sont également évocateurs du prognostc de la durée de vie des patientes atteintes du cancer du sein selon après une rechute et/ou des métastases de leur cancer.

Affiliated with

Also associated with

Rating

Assay for ykl-40 as a marker for degradation of mammalian... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Assay for ykl-40 as a marker for degradation of mammalian..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Assay for ykl-40 as a marker for degradation of mammalian... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1791965