Assay method

Details Assay method Assay method

G - Physics

01

N

G01N 33/58 (2006.01) A61K 51/00 (2006.01) G01N 33/533 (2006.01) G01N 33/534 (2006.01) G01N 33/566 (2006.01) G01N 33/569 (2006.01) G01N 33/60 (2006.01)

Patent

CA 2328634

An assay method for determining whether an agent is capable of modulating the interaction of CCR5 with gp120 is disclosed. The method comprises incubating the agent with CCR5 and gp120 to form a first reaction mixture; and determining whether said agent modulates the interaction of CCR5 with gp120; wherein said gp120 is associated with CD4. In particular, the interaction is a low affinity binding.

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