Assay method using agglutination of antigen-antibody complex...

G - Physics – 01 – N

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G01N 33/53 (2006.01) G01N 33/50 (2006.01) G01N 33/541 (2006.01)

Patent

CA 1091149

"MOUSE SERUM" ABRIDGEMENT (ABSTRACT) In the analysis of liquids, particularly biological liquids such as serum or urine, there is used as a reagent mouse serum or a component of mouse serum. The component has the ability to combine with antibody antigen complexes (but not free antibody or antigen) and to combine with IgG and IgM. It differs markedly from human Ciq in that it remains active at high pH and in the presence of certain substances known to destroy human Ciq. It is a very broadly applicable reagent in immunoassays, and particularly useful in techniques involving agglutination at latex particles.

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