Assay methods and compositions for detecting serum...

Details Assay methods and compositions for detecting serum... Assay methods and compositions for detecting serum...

G - Physics

01

N

G01N 33/573 (2006.01) C07K 16/40 (2006.01) C12Q 1/37 (2006.01) C12Q 1/56 (2006.01) G01N 33/577 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2112702

The invention describes diagnostic methods and compositions for determining the amount of protease in a body fluid sample. In particular, the invention detects proteases by a method in which both a reversible inhibitor of the protease and an irreversible inhibitor of interfering protease during the detection step are employed to increase the sensitivity of the enzyme capture assay. The assay detects normal serum levels of activated protein C.

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