G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01)
Patent
CA 2418377
Novel assay methods for screening compounds or identifying compounds useful for treating gastroesophageal disease (GERD) are described, which involve determining the level of or presence of an interaction between the test compound and a polypeptide sequence comprising a portion of the extracellular domain of the junctional protein E-cadherin or a related polypeptide sequence.
L'invention concerne de nouvelles méthodes d'analyse permettant de sélectionner ou d'identifier des composés utilisés pour traiter le reflux gastro-oesophagien pathologique (RGOP). Ces méthodes consistent à déterminer le niveau ou la présence d'une interaction entre le composé d'essai et une séquence polypeptidique comprenant une portion du domaine extracellulaire de la protéine de jonction cadhérine E ou une séquence polypeptidique apparentée.
Orlando Roy C.
Tobey Nelia A.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The Administrators Of The Tulane Educational Fund
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