Assaying method for primary amines using aromatic dialdehydes

G - Physics – 01 – N

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G01N 33/68 (2006.01) C07D 209/62 (2006.01) C07D 477/00 (2006.01) G01N 33/52 (2006.01)

Patent

CA 1293590

ABSTRACT Primary amines are assayed by providing a substituted or unsubstituted naphthalene-2,3-dicarboxyaldehyde reac- tive with primary amines, reacting the substituted or unsubstituted naphthalene-2,3-dicarboxyaldehyde with at least one primary amine analyte and cyanide ion to form an adduct amenable to fluorometric or electrochemichal assaying techniques and fluorometrically or electroche- mically assaying said adduct. The method according to the invention enables assaying of trace concentrations of analytes containing one or more primary amino groups.

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