C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/55 (2006.01) C07H 21/00 (2006.01) C07K 14/40 (2006.01) C07K 16/14 (2006.01) C07K 16/40 (2006.01) C07K 19/00 (2006.01) C12N 9/10 (2006.01) C12N 9/12 (2006.01) C12N 9/16 (2006.01) C12N 9/96 (2006.01) C12N 15/31 (2006.01) C12N 15/54 (2006.01) C12Q 1/18 (2006.01) C12Q 1/44 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2251593
The present invention relates to rapid, reliable and effective assays for screening and identifying pharmaceutically effective compounds that specifically inhibit the biological activity of fungal GTPase proteins, particularly GTPases involved in cell wall integrity, hyphael formation, and/or other cellular functions critical to pathogenesis. Another aspect of the present invention relates to novel Candida genes and gene products.
La présente invention concerne des dosages rapides, fiables et efficaces pour détecter et identifier des composés pharmaceutiquement efficaces qui inhibent spécifiquement l'activité biologique des protéines fongiques activant la GTPase, notamment les GTPases affectant l'intégrité de la paroi cellulaire, la formation mycélienne et/ou d'autres fonctions cellulaires décisives pour la pathogenèse. Un autre aspect de la présente invention concerne de nouveaux gènes Candida et produits géniques.
Berlin Vivian
Damagnez Veronique
Levin David E.
Ohya Yoshikazu
Smith Susan E.
Borden Ladner Gervais Llp
Mitotix Inc.
The Johns Hopkins University
LandOfFree
Assays and reagents for identifying anti-fungal agents, and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Assays and reagents for identifying anti-fungal agents, and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Assays and reagents for identifying anti-fungal agents, and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1730708