Assays for detecting and quantifying contaminants and...

Details Assays for detecting and quantifying contaminants and... Assays for detecting and quantifying contaminants and...

G - Physics

01

N

G01N 33/53 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2353687

An assay for detecting and quantifying at least one contaminant in a sample comprising (a) mixing the sample with liposomes having a known capture efficiency so as to form a mixture; (b) isolating the liposomes including the contaminant bound liposomes from the mixture; (c) detecting and metering the at least one contaminant; (d) determining the concentration of the at least one contaminant in the sample by multiplying the liposomes capture efficiency with the quantity of the at least one contaminant determined in (c), wherein the lipid composition of the liposomes possesses affinities with said at least one contaminant so that if the sample contains contaminants, at least a portion of the at least one contaminant is bound to the liposomes. The assays of the present invention are advantageously simple and inexpensive to perform and are particularly suitable for tests performed outside of sophisticated laboratories.

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