Assays for immunosuppressants

Details Assays for immunosuppressants Assays for immunosuppressants

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12Q 1/34 (2006.01) C12Q 1/66 (2006.01) G01N 33/49 (2006.01)

Patent

CA 2179890

Quantitative reporter gene assays allowing for highly precise measurements of immunosuppressants in bodily fluids are provided, e.g., an IL-2 reporter gene assay for measuring blood levels of immunosuppressive cyclosporins and ascomycins (e.g., cyclosporin A and FK-506), and a c-jun reporter gene assay for measuring blood levels of immunosuppressive rapamycins.

Analyses quantitatives de gènes reporteurs permettant des mesures extrêmement précises des immunosuppresseurs dans des fluides organiques, par exemple une analyse du gène reporteur IL-2 destinée à mesurer la concentration sanguine en cyclosporines et ascomycines à effet immunosuppresseur (par exemple la cyclosporine A et FK-506), et une analyse du gène reporteur c-jun destinée à mesurer la concentration sanguine en rapamycines à effet immunosuppresseur.

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