Assessing neuronal damage from blood samples

Details Assessing neuronal damage from blood samples Assessing neuronal damage from blood samples

G - Physics

01

N

G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2520945

Neuronal damage is detected by providing a biological sample derived from the subject, detecting in the sample the presence of a neurofilament subunits or their breakdown products, and correlating the presence and level of the neurofilament subunits and their breakdown products detected with the degree of neuronal injury.

Selon l'invention, pour détecter les lésions neuronales, on utilise un prélèvement biologique issu d'un sujet, on détecte dans le prélèvement la présence de sous-unités d'un neurofilament ou de leurs produits de fractionnement et on corrèle la présence et le taux des sous-unités du neurofilament et de leurs produits de fractionnement détectés avec le degré de lésion neuronale.

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