Assessment and reduction of risk of graft-versus-host disease

C - Chemistry – Metallurgy – 40 – B

Patent

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Details

C40B 40/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2650507

Methods of assessing and reducing risk of graft versus host disease (GVHD) based on gene expression profiling are described, as well as methods of selecting a suitable transplant donor. Corresponding reagents and kits are also described.

L'invention concerne des procédés permettant d'évaluer et de réduire le risque de réaction du greffon contre l'hôte (GVHD) sur la base d'un profilage d'expression génique ainsi que des procédés de sélection d'un donneur de greffe approprié. L'invention concerne également les réactifs et kits correspondants.

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