Assessment of bone cell activity

C - Chemistry – Metallurgy – 12 – M

Patent

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Details

C12M 3/04 (2006.01) C03C 17/22 (2006.01) C04B 41/50 (2006.01) C12M 1/34 (2006.01) C12N 5/00 (2006.01) C12Q 1/02 (2006.01) G01N 15/14 (2006.01) G01N 33/48 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2152477

A calcium phosphate based thin film on which bone cells may be cultured to permit evaluation of bone cell functional properties comprises calcium phosphate entities which provide for varying degrees of resorption of the calcium phosphate entities in evaluating the functional properties. The film is sufficiently thin that resorpti.on of the entities can be detected. Such film, as applied to a support, is a very useful analytical component for evaluating such bone cell functional characteristics. An analytical device, which may be used in an analytical kit, can be provided having a plurality of wells with the devices located at the bottom thereof. A process is provided for making the film and especially the film which has a combination of calcium hydroxyapatite with tricalcium phosphate.

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